Entraining Central and Peripheral Circadian Rhythms
“Desynchronization between the central and peripheral clocks by, for instance, altered timing of food intake, can lead to uncoupling of peripheral clocks from the central pacemaker and is, in humans,...
View ArticleMeal timing and peripheral circadian clocks
More on why breakfast in the morning, with light onset is important to avoid circadian desynchrony. FOOD is excellent at entraining peripheral circadian clocks: if you restrict animals to one meal per...
View ArticleCircadian Disruption Impairs Survival in the Wild
…just read that huge disasters, ranging from Exxon Valdez to Chernobyl, may have been due, in part, to ignorance of basic principles of circadian rhythms. Gravitas. The master circadian clock, or...
View ArticleLIGHT, Leptin, and Environmental Mismatch
For a long time, the melanocortin system was basically thought to control the color of skin and hair. It still does, and many redheads are redheaded due to polymorphisms in one of the melanocortin...
View ArticleCarbs: Low vs. Lower
Carbs: low is good; is *lower* better? this study suggests “nope” http://t.co/5MATDl8Msr — Bill Lagakos (@CaloriesProper) February 27, 2015 This was met with much backlash from the low carb...
View ArticleNon-celiac gluten sensitivity
Gluten is protein, not carbs. A gluten-free diet is frequently low-carb, because most dietary gluten comes in the form of bread (and wheaty foods). But believe it or not, bread is an incredibly...
View ArticleGood calories
Nuts are good calories. I’m not a big fan of the omega-6 fatty acid linoleate, but that’s largely in the context of processed foods and confectioneries, where it’s more than likely no longer in it’s...
View ArticleMeal frequency, intermittent fasting, and dietary protein
Dietary protein “requirements” are some of the most context-dependent nutrient levels to decipher, and depend largely on energy balance and even meal frequency. An objective look at intermittent...
View ArticleSaturated fat, cholesterol, and carbohydrates
“You catch more flies with honey…” ^^^good policy in general, but especially for debating in the realm of nutritional sciences. A short while back, Nina Teicholz discussed low carb ketogenic diets...
View ArticleDawn PheNOMNOMNOM
Many pre-diabetic, diabetic, and insulin resistant people have used the low carbohydrate diet to successfully manage their blood glucose levels. It just plain works. FACT (P<0.05). However, a...
View ArticleA brief explanation of Hall et al., ie, THE LOW CARB WAR
“Examination of acute shifts in energy balance by selectively reducing calorie intake from one macronutrient.” Intro (1/2): please don’t read this study with the media headlines in your mind. Don’t...
View ArticleHall et al., THE FIRST SIX DAYS (update)
Some people say the study design was rigged to favor the Low Fat diet (LF), which is dirty business but not exactly criminal; sometimes, this happens in science. The claims go something like this:...
View ArticleSome nuances of Intermittent Fasting
Intermittent fasting (IF) is not a universal panacea, regardless of whether you’re not eating anything at all for a few days each week/month or just restricting your feeding window to a few hours per...
View Article“Insulin Dynamics”
This one has a bit for everyone. Relationship of Insulin Dynamics to Body Composition and Resting Energy Expenditure Following Weight Loss (Hron et al., 2015) I think study was actually done a few...
View ArticleThe “Insulin Index”
Similar to the glycemic index, which is an estimate of the rise in blood glucose after eating a particular food, the insulin index is an estimate of the rise in insulin after eating a particular food....
View ArticleEpigenetics & Circadian Biology: Prader-Willi
I came across a recent study on a mouse model of Angelman Syndrome (an epigenetic disorder), and wasn’t surprised to learn there’s a strong circadian component to it. Epigenetics are one of the main...
View ArticleHANGRY!
So the theory goes: high carb meal -> blood glucose spike -> insulin spikes a little too hard -> hypoglycemia -> hunger, so you eat to replenish blood glucose. In the original theory of...
View ArticlePersonalized Nutrition by Prediction of Glycemic Responses
“please stop asking gurus how many carbs you need to optimize health” An interesting paper came out recently by Zeevi et al. (2015), showing, in part, that we’re all unique snowflakes (in some...
View ArticlePersonalized Nutrition II
More on Zeevi et al. (2015) (this is a follow-up to part 1) I like this study a lot, or at least the fundamentals… or new tools that it might bring to the table. Like, we know sleep and physical...
View ArticleNew low carb protein bars
Warning: this post isn’t #Paleo Certified™. It’s more about convenience, choosing the lesser evil. Quest Nutrition led the charge in low carb, high protein, fibre-rich bars. “Fibre-rich” is really...
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